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Rare! To Provide A Safe Basis For The Application Of UVC-LED To The Human Body, Japan's Mie University Has Done Such An Experiment

Feb 14, 2022

Jaapani Mie ülikooli uurimisrühm on leidnud, et sebrakala varaseid embrüoid (embrüod mitu tundi pärast viljastamist) saab ohutult kiiritada 278 nm UVC-ga.


UVC-Umbes 260 nm laiusega LED-e kasutatakse steriliseerimiseks, kuna need kutsuvad esile ja inaktiveerivad bakterite ja viiruste DNA kahjustusi. Enamik praegustest uuringutest keskendub UVC mõjule, mille lainepikkus on alla 240 nm (207 nm, 222 nm, 233 nm) uue koroonaviiruse tapmisele. Siiski on vähe uuringuid organismide toksilisuse, ohutuse ja UVC-kiirgusele reageerimise kohta umbes 280 nm.

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Therefore, this time, a total of 16 irradiation doses were set in the range of 0.5 to 60 mJ/cm² using the irradiation device developed by the research group to irradiate 278 nm UVC, and zebrafish embryos were directly irradiated.


After 3 days of irradiation, the researchers evaluated the survival rate, hatching rate, heart rate, deformity rate, etc. of zebrafish embryos. The results found that all embryos remained alive under the irradiation dose below 4.5mJ/cm². However, when the dose reached 7.5 mJ/cm², the deformity rate significantly increased to 82 percent , and the survival rate decreased to 37 percent . Embryo death was observed if the dose was increased to 10 mJ/cm² and above.


Based on the above experimental results, the researchers determined that there is a biological defense system inside the zebrafish embryo, which can resist the damage caused by UVC irradiation to the greatest extent, and the limit dose that can resist UVC irradiation is 4.5 mJ/cm².


The researchers believe that the biological defense mechanism of zebrafish against UVC-induced DNA damage is that after zebrafish embryos are treated with UVC at a dose of 4.5 mJ/cm², the p53 signaling pathway in cells is immediately and urgently activated. Arrest, DNA repair, cell division/proliferation and damaged cell death in rapid response to stress. In addition, after 3 days of recovery, p53 variability was attenuated and instead activated the STAT signaling pathway, which continued to repair damaged DNA.


Selle teema uurimistulemused annavad teadusliku aluse inimkehale rakendatud UVC{0}}LED-i ohutusele. Samal ajal leidis uurimisrühm, et UVC sobib bakterite ja viiruste, sealhulgas koroonaviiruse desinfitseerimiseks, samuti vesiviljeluse desinfitseerimiseks.


"Experts say UV" believes that: at the application level, the sterilization experience of UVC-LED is difficult to intuitively perceive, and consumers will have concerns about safety when using it. brings confidence.


GMKJ LED-tehnoloogia on sügavalt seotud tervislike ja nutikate valgusallikatega, pakkudes turule täielikku valikut UVA UVB UVC LED-i, infrapuna-IR LED VCSEL-i tooteid ja lahendusi, ning omab sadu kvaliteetseid{0}}partnereid kodu- ja välismaistes riikides. turgudel, et ühiselt edendada valgustehnoloogia kasutamist tervisliku ja nutika elu loomiseks. põhjus.